Premium Clot Activator Tube for Enhanced Blood Sample Collection

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Customization: Available
Transport Package: Box
Trademark: LIKANG-CHENGWU
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  • Premium Clot Activator Tube for Enhanced Blood Sample Collection
  • Premium Clot Activator Tube for Enhanced Blood Sample Collection
  • Premium Clot Activator Tube for Enhanced Blood Sample Collection
  • Premium Clot Activator Tube for Enhanced Blood Sample Collection
  • Premium Clot Activator Tube for Enhanced Blood Sample Collection
  • Premium Clot Activator Tube for Enhanced Blood Sample Collection
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Overview

Basic Info.

Model NO.
LIKANG
Origin
China
HS Code
30021001
Production Capacity
50000000

Product Description

Premium Clot Activator Tube for Enhanced Blood Sample Collection
Product Description
                              Clot Activator Tube: Optimizing Serum Preparation for Diagnostic Precision
 
A clot activator tube is a specialized medical device engineered to expedite blood coagulation, enabling the rapid and efficient separation of serum from whole blood for diagnostic testing. Widely utilized in clinical laboratories, hospitals, and research settings, these tubes play a pivotal role in ensuring the accuracy and timeliness of various blood analyses, from routine chemistry panels to complex serological assays.

Design and Operational Principle

Clot activator tubes are typically composed of a sterile, vacuum-sealed plastic (e.g., PET) or glass vessel with a secure rubber stopper. The core feature is the inclusion of clot-accelerating agents inside the tube, which initiate the coagulation cascade. Common activators include:
 
  • Silica-based particles: These physically stimulate platelet aggregation, kickstarting clot formation.
  • Thrombin or tissue factor: Biochemical agents that directly facilitate the conversion of fibrinogen to fibrin, accelerating clot development.
  • Glass fibers or beads: These enhance contact activation of clotting factors, ensuring consistent and rapid coagulation.
    Many tubes also incorporate a gel separator-a dense, inert polymer layer that, upon centrifugation, forms a barrier between the serum (upper layer) and cellular components (lower layer), preventing recontamination and ensuring pure serum collection.

Workflow and Applications

The primary function of a clot activator tube is to produce serum-the cell-free, protein-rich fluid essential for tests requiring analyte measurement in plasma-derived fluids. The process unfolds as follows:
 
  1. Blood Collection: The pre-vacuumed tube draws a precise volume of blood via a sterile needle, ensuring standardized sample quantity.
  2. Activation and Clotting: After collection, the tube is gently inverted 5-8 times to mix blood with the clot activator, triggering coagulation. This reduces clotting time from hours (in plain tubes) to 5-15 minutes.
  3. Centrifugation: The tube is spun at high speed, causing the gel separator to migrate between serum (≈30-40% of total volume) and the clotted cells. This separates the serum into a clear, ready-to-analyze fraction.
  4. Serum Retrieval: The supernatant serum is transferred to a secondary container for testing, while the clot and gel are safely discarded.

Key Benefits

  • Efficiency: Dramatically reduces pre-analytical turnaround time, critical for urgent or high-throughput testing environments.
  • Sample Purity: The gel separator ensures minimal cellular contamination, preserving serum integrity and preventing hemolysis or lipid interference in results.
  • Standardization: Consistent activator concentrations and vacuum levels ensure uniform clotting across samples, enhancing inter-laboratory reproducibility.
  • Safety: Sterile, leak-proof designs and compatibility with closed systems minimize the risk of healthcare worker exposure to biohazards.

Regulatory and Quality Standards

Clot activator tubes are categorized as Class II medical devices in most jurisdictions (e.g., FDA in the U.S., CE IVDR in the EU), subject to strict manufacturing and quality control standards (e.g., ISO 13485). They must undergo rigorous validation to ensure activator efficacy, tube sterility, and gel separator performance. Common applications include:
 
  • Clinical Chemistry: Monitoring electrolytes, enzymes, and metabolites (e.g., glucose, creatinine).
  • Serology: Detecting antibodies for infectious disease screening (e.g., HIV, hepatitis).
  • Endocrinology: Measuring hormone levels (e.g., thyroid-stimulating hormone).
  • Pharmacology: Therapeutic drug monitoring to assess medication efficacy or toxicity.
 
In summary, clot activator tubes are indispensable tools in modern diagnostics, bridging the gap between blood collection and accurate laboratory results. Their design prioritizes speed, precision, and safety, making them a cornerstone of healthcare workflows worldwide.
Product Parameters

Pro-coagulation Tube aims to obtain serum specimen, which is used for biochemistry and immunology tests. The interior wall is finely coated with coagulant which may promote the blood coagulation after collection.The appropriate amount of coagulant make blood coagulation in a relatively short time, avoiding potential hemolysis problem which caused by too rapid clotting. Finally, transparent serum can be separated after centrifugation.

Detailed Photos

Premium Clot Activator Tube for Enhanced Blood Sample Collection

 

Our Factory

Premium Clot Activator Tube for Enhanced Blood Sample Collection

Our Company
Premium Clot Activator Tube for Enhanced Blood Sample Collection
Premium Clot Activator Tube for Enhanced Blood Sample Collection
Shippment

Premium Clot Activator Tube for Enhanced Blood Sample Collection





 

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